The Prophet We Ignored:

Why Sepsis Diagnoses Dropped 50% But Deaths Keep Rising

November 07, 2025

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A Message from Dr. McMillan

Sepsis remains one of the most time-critical conditions in hospital medicine, with strict early-action protocols proven to reduce deaths. Yet, what if post-pandemic sepsis, with population immune suppression, no longer fits the old definitions? When inflammation and clotting patterns have changed, our familiar checklists may fail. If we don’t redefine what sepsis looks like today, the outcomes are unlikely to be good.

Dr. Philip McMillan

In this week's November 7th, 2025 update:

  • Covid-19: Sepsis diagnoses dropped but deaths keep rising

  • Vejon: This week’s featured Vejon video

  • Health: A few thousand steps a day can reduce Alzheimer’s risk

  • Infographic: The prophet we ignored

  • News: Medical news in brief

  • Education: McMillan ROOT spike detox protocol

    Read time: 6 minutes

FEATURE ARTICLE

COVID-19

  • Sepsis diagnoses dropped 50% while deaths remained elevated, suggesting patients dying from sepsis-like syndromes are being miscoded.

  • Geert Vanden Bossche predicted mass vaccination during pandemic would accelerate viral evolution; outcome confirmed fastest variant evolution recorded.

  • Five factors converge: original antigenic sin, IgG4 dominance, T-cell evasion, interferon suppression, and accelerating variant evolution.

  • mRNA vaccines suppress interferon pathway, potentially accelerating cancer metastasis and enabling silent viral replication via exosome circulation.

Why this is important: Healthcare systems may face a diagnostic crisis they cannot see coming. Disease patterns are shifting beneath standard protocols: immune suppression from repeated vaccinations could enable silent viral replication until catastrophic organ failure occurs. Without recognizing these atypical presentations, medicine will misdiagnose patients until systems become overwhelmed by what appears to be inexplicable deaths.

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HEALTH

Even a Few Thousand Steps a Day Can Reduce Your Risk of Alzheimer’s
Author: Edf Hogervorst, Loughborough University

  • Physical activity reduced misfolded tau proteins in Alzheimer's patients, cutting dementia signs by half, though it didn't affect amyloid plaques.

  • Benefits appeared at just 3,000 steps daily, with optimal protection at 5,000-7,500 steps, making this achievable for sedentary seniors.

  • Exercise may protect brains through multiple pathways: cardiovascular health, increased blood flow, and hormones like irisin that reduce inflammation.

  • Broader UK studies found 25-50% dementia risk reduction with regular walking, with benefits appearing even in those already showing symptoms.

Why this is important: Walking just 3,000 steps daily can significantly reduce Alzheimer's risk by targeting tau proteins—the toxic tangles most linked to memory decline. This matters because the protection plateaus at 5,000-7,500 steps, making dementia prevention achievable for older, sedentary people without demanding extreme fitness regimens.

INFOGRAPHIC

EDUCATION

McMillan ROOT Spike Detox Protocol

You don’t have to settle for feeling anything less than your best. The McMillan ROOT Spike Detox Protocol is designed to give you a clear roadmap to better health and lasting results. Complete our survey, get the link on submission to book a Check-In meeting with Dr McMillan and start your journey back to health. Note that all meetings are scheduled in UK time.

MEDICAL NEWS IN BRIEF

NEWS HIGHLIGHTS

🚥 Could Pain Medication Be Causing Your Headaches? Painkillers can perpetuate the very headaches they're meant to cure, a medical irony affecting 1-2% of the population. Regular use, even within safe doses, may trigger chronic pain. Recognition is critical: cessation under medical guidance often reverses the condition, but patients rarely suspect their relief has become their problem.

🚥 Protein-Based Gel Restores Dental Enamel and Could Advance Tooth Repair: Half the world battles tooth decay because enamel can't regenerate, until now. This gel reverses permanent damage by rebuilding enamel from within, not just masking erosion. It transforms an irreversible biological weakness into something fixable, potentially preventing infection, tooth loss, and the systemic diseases linked to oral health. [SOURCE]

🚥 Why Does Your Doctor Seem So Rushed and Dismissive? Your rushed doctor visits aren't about poor bedside manner; they're symptoms of broken healthcare economics forcing physicians to see too many patients too quickly. This systemic overload directly worsens your medical outcomes, increases diagnostic errors, and drives doctor burnout. The prescription: patients and physicians must advocate together for workload reforms that restore quality care.

🚥 Early-Stage Clinical Trial Demonstrates Promise of Intranasal Influenza Vaccine in Generating Broad Immunity: A nasal spray vaccine could finally interrupt flu transmission at its source - the respiratory tract - rather than merely reducing symptoms after infection takes hold. Unlike standard shots, this H5N1 candidate primes defenses where the virus enters, potentially blocking spread between people while offering protection against multiple evolving strains during future pandemics. [SOURCE]

🚥 The Surprising Link Between Gut and Brain Rhythms: Intestinal contractions and brain blood vessels synchronize using identical mathematical rhythms, revealing unexpected unity between distant organ systems. This discovery could transform treatment approaches for both neurological conditions and digestive disorders by targeting shared coordination mechanisms rather than isolated symptoms. [SOURCE]

🚥 Common Gene Variant Linked to Higher Heart Disease Risk in People With African Ancestry: Black patients develop a specific heart failure condition at twice the rate of white patients; a gap that clinical factors couldn't explain. Researchers discovered a single gene mutation present in 17% of people with African ancestry accounts for one-fifth of this disparity, opening pathways for targeted screening and treatment. [SOURCE]

BOOK NOOK

Set within a child’s nose, ‘Humming Heroes’ features a family of Lymphocytes led by a wise Mother, brave Father, determined Brother, and heroic Baby, confronting invading microorganisms. The story takes an imaginative turn, when a humming melody combines with the Lymphocytes’ song to repel the invaders and restore inner harmony.

"Disease X: Are You Prepared?" is your comprehensive guide to navigating the uncertain future of global health. Drawing from experience and the latest scientific insights, this book offers:

  • Practical strategies for personal and community preparedness.

  • Lessons learned from COVID-19 and other outbreaks.

  • Actionable steps to boost resilience against emerging health threats.

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